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Communication | Regular issue | Vol 45, No. 8, 1997, pp.1451-1455
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7849
Asymmetric Synthesis with Chiral Hydrogenolysable Amines : A New Route to Enantiomerically Pure Amino Diols

Fabienne Segat, Olivier Lingibé, Bernadette Graffe, Marie-Claude Sacquet, and Gérard Lhommet*

*Université P. et M. Curie, Laboratoire de Chimie des Hétérocycles URA 408, 4, Place Jussieu - case 43 F-75252 Paris Cedex 05, France


Enantiomerically pure amino diols are obtained via diastereoselective reduction of chiral enamino and imino esters (3a), (3b), and (3c).