Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 45, No. 8, 1997, pp.1551-1557
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7847
Ring Transformation of Fused Pyridazines. VI. Construction of 3-(2-Pyridyl)indole Skeleton by Means of N-N Bond Cleavage Reaction of Fused Pyridazines with Ynamines

Ken-ichi Iwamoto,* Etsuo Oishi, Tomonobu Sano, Ayako Tsuchiya, Yumiko Suzuki, Takeo Higashino, and Akira Miyashita

*Schol of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, Japan

Abstract

We established a new N-N bond cleavage reaction of pyridazino[4,5-b]indoles with ynamines to form 3-(2-pyridyl)indoles. The latter are easily converted to 3-(2-piperidyl)indoles, which are key intermediates for the synthesis of indole alkaloids.