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Communication | Regular issue | Vol 45, No. 5, 1997, pp.863-866
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7790
Triethylborane-mediated Atom Transfer Cyclization of N-Allylic α-Iodo-acetamides: A Convenient Synthesis of β-Iodomethyl-γ-lactams

Masazumi Ikeda, Hirotaka Teranishi, Noriko Iwamura, and Hiroyuki Ishibashi*

*Faculty of Pharmaceutical Scicences, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-0934, Japan


In the presence of triethylborane, N-allylic α-iodoacetamides underwent atom tranfer cyclization to give β-iodomethyl-γ-lactams in high yields.