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Communication | Regular issue | Vol 45, No. 5, 1997, pp.857-861
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7783
Imidazo[4,5-e][1,2,4]triazocine: A Novel 5:8-Fused Ring System Riddled With Rearrangements

Friedrick N. Burnett and Ramachandra S. Hosmane*

*Laboratory for Drug Design and Synthesis, Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21228, U.S.A.


Attempts to synthesize the title 5:8-fused heterocyclic ring system resulted in a number of novel opportunistic rearrangements and transformations. There is, however, some evidence to believe that one of these rearrangements might proceed through the transient intermediacy of this ring system.