Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 45, No. 5, 1997, pp.835-839
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7764
C2-Alkylaminopenem Synthesis

Takumi Yamasaki, Hiroshi Kadoi, and Isao Nagakura*

*Chemical Process Development Laboratory, Drug Substance Manufacturing Plant, Pfizer Pharmaceuticals, 5-Gochi, Taketoyo-cho, Chita-gun, Aichi, Japan


A simple synthesis of C2-dialkylaminopenems is described. Azetidione glyoxylate has been cyclized to C2-aminopenem, via an intramolecular sulfide-contraction reaction.