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Note | Regular issue | Vol 45, No. 5, 1997, pp.955-962
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7744
An Original Way for Synthesis of New Nitrobenzothiadiazole Derivatives

Patrice Vanelle,* Céline Tremblais Liegeois, Jacobine Meuche, José Maldonado, and Michel P. Crozet

*Laboratorie de Chimie Organique, Université d' Aix-Marseille 2, Faculté de Pharmacie, 27 Bd. Moulin, 13385 Marseille Cedex 05, France


The C-alkylation reaction of 4-chloromethyl-7-nitro-2,1,3-benzothiadiazole with 2-nitropropane anion which is shown to proceed by an SRN1 mechanism is an original way for the synthesis of new 2,1,3-benzothiadiazoles.