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Paper | Regular issue | Vol 45, No. 4, 1997, pp.735-744
Published online, 1st January, 1970■ Reactivity of 1,3-Di-tert-butylaziri-dinones with Phenyl Substituents. A New Fragmentation of α-Lactams
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7739
■ Reactivity of 1,3-Di-tert-butylaziri-dinones with Phenyl Substituents. A New Fragmentation of α-Lactams
Masako Shimazu, Yasuyuki Endo,* and Koichi Shudo
*Faculty of Pharmaceutical Sciences, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113, Japan
Abstract
Several isolable aziridinones with bulky substituents were prepared and their reactions with nucleophiles, i.e., methanol, sodium methoxide and benzylamine, were investigated. A novel fragmentation of aziridinones having a phenyl group on the C3 moiety was found.
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