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■ 6-Acetyl-8-hydroxy-2,2-dimethylchromene, an Antioxidant in Sunflower Seeds; Its Isolation and Synthesis and Antioxidant Activity of Its Derivatives

Hideyuki Tsuda, Youichi Ishitani, Yoshiyuki Takemura, Yoshiaki Suzuki, and Tadahiro Kato*

*Department of Chemistry, Faculty of Science, Science University of Tokyo, Kagurazaka 1-3, Shinjuku-ku, Tokyo 162-8601, Japan

Abstract

By the guide of assay toward inhibition of photooxidation of β-carotene, 6-acetyl-8-hydroxy-2,2-dimethylchromene (1) was isolated from sunflower seeds. In addition to 1, the analogous compounds possessing the chromene (chromane) skeleton were synthesized and their antioxidant activities were examined.