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Communication | Special issue | Vol 46, No. 1, 1997, pp.21-26
Published online, 1st January, 1970
DOI: 10.3987/COM-96-S3
A New Synthesis of (-)-Aphanorphine by an Enantioconvergent Tactic

Masahiro Shimizu, Takashi Kamikubo, and Kunio Ogasawara*

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

A new route to (-)-aphanorphine, isolated from the blue-green alga Aphanizomenon flos-aquae, has been devised by employing an enantioconvergent tactic making use of both enantiomeric starting materials.