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Paper | Regular issue | Vol 45, No. 4, 1997, pp.707-713
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7730
One-Pot Synthesis of 1,10-Dihydro-2H-imidazo[3,4-a]quinazolin-1-ones from 3-Acyl-1,2-dihydrocinnoline-1,2-dicarboximides

Kazuyoshi Seguchi* and Satoko Tanaka

*Faculty of Human Environmental Sciences, Mukogawa-Women's University, 11-68 Koushien Kyuban-Cho, Nishinomiya, Hyogo 663-8179, Japan


3-Substituted 1,10-dihydro-2H-imidazo[3,4-a]quinazolin-1-ones were prepared from 3-acyl-1,2-dihydrocinnoline-1,2-dicarboximides and piperidine in DMSO in moderate yields via Michael additions, skeletal rearrangements, and subsequent decarboxylation.