Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 45, No. 2, 1997, pp.339-346
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7680
A Simple and Efficient Synthetic Method for Fluorine-containing Benzo[h]qunolines

Etsuji Okada,* Hiroshi Tone, Norikado Tsukushi, Yoshihiro Otsuki, Hiroshi Takeuchi, and Masaru Hojo

*Department of Chemical Science and Engineerring, Faculty of Engineering, Kobe University, Rokkodai-cho, Nada-ku, Kobe 657-8501, Japan

Abstract

N-Propargyl-2,4-bis(trifluoroacetyl)-1-naphthylamine (2), prepared from N,N-dimethyl-2,4-bis(trifluoroactyl)-1-naphthylamine (1) and propargylamine, undergoes ring forming reaction with amines, thiolates and alcoholates under mild conditions to afford the corresponding 6-trifluoroacetyl-4-trifluoromethylbenzo[h]quinolines (3) in excellent yields.