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Note | Regular issue | Vol 45, No. 1, 1997, pp.177-180
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7665
Synthesis and the Absolute Configuration of PQ-8, a C14-Polyacetylene Compound Isolated from Panax quinquefolium

Mitsuru Satoh, Naoki Takeuchi, and Yasuo Fujimoto*

*Showa Pharmaceutical University, 3-3165, Higashi-tamagawagakuen, Machida, Tokyo 194-8543, Japan


PQ-8 (5), a C14-polyacetylene compound isolated from Panax quinquefolium, was synthesized starting from L-(+)-diethyl tartrate. The absolute stereostructure of PQ-8 was confirmed as (6R,7S)-6,7-epoxytetradeca-1,3-diyne.