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Communication | Regular issue | Vol 45, No. 1, 1997, pp.15-18
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7654
High Pressure Diels-Alder Reactions of Pyridones with Cyclooctyne

Kiyoshi Matsumoto,* Mona Ciobanu, Maki Yoshida, and Takane Uchida

*Graduate School of Human and Environmental Studies, Kyoto University, Yoshida-Nihonmatsu-cho, Sakyo-ku, Kyoto 606-8501, Japan


The high-pressure (0.8 GPa) Diels-Alder reactions of N-methyl-2(1H)-pyridones with cyclooctyne have afforded the corresponding stable bridged tricyclic 1:1 cycloadducts in moderate to good yields.