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Communication | Regular issue | Vol 43, No. 12, 1996, pp.2553-2556
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7632
Synthesis of (-)-Vertinolide

Keizo Matsuo* and Yusuke Sakaguchi

*Faculty of Pharmaceutical Sciences, Kinki University, 3-4-1, Kowakae, Higashi-Osaka 577-8502, Japan

Abstract

(-)-Vertinolide, a β-tetronic acud derivative isolated from Verticillium intertextum as one of the mycotoxins, was synthesized starting from (R)-lactic acid as the chiral source using Seebach’s chiral self-reproduction method.