HETEROCYCLES

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

■ Synthesis of Vinca Alkaloids and Related Compounds. Part LXXXII. An Unexpected Neber-Type Rearrangement

István Moldvai, Csaba Szántay Jr., and Csaba Szántay

*Central Research Institute for Chemistry, Hungarian Academy of Sciences, H-1525 Budapest, P.O.Box 17, Hungary

Abstract

(+)-15-Oxo-14,15,-dihydroeburnamenine (2) was tansformed into oxime (3). On treatment with acetic acid or Raney Ni, oxime (3) afforded the 15-acetamidovincamone isomers (4,5) and the 15β-amino derivatives (12,13), respectively. The oxime acetate (14) and the oxime ether (15) were also prepared.