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Communication | Regular issue | Vol 43, No. 7, 1996, pp.1375-1379
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7475
Highly Effective Procedure for Introduction of Amino Group into the 2-Position of Imidazole Ring

Ikuo Kawasaki, Norio Taguchi, Youko Yoneda, Masayuki Yamashita, and Shunsaku Ohta*

*Kyoto Pharmaceutical University, Misasagi, Yamashina, Kyoto 607-8414, Japan

Abstract

Procedures for the preparation of 2-amino- and 2-arylaminobenzimidazoles were developed, and one of the efficient procedure was applied ot the synthesis of preclathridine A, a marine imidazole alkaloid isolated from a sponge.