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Paper | Regular issue | Vol 43, No. 6, 1996, pp.1287-1300
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7463
Chiral Synthesis of Furanosesquiterpene, (+)-Ipomeamarone

Keizo Matsuo,* Takahiko Arase, Shigetoshi Ishida, and Yusuke Sakaguchi

*Faculty of Pharmaceutical Sciences, Kinki University, 3-4-1, Kowakae, Higashiosaka, Osaka 577, Japan


(+)-Ipomeamarone, a furanosesquiterpene isolated from mold-damaged sweet potato (Ipomea batatas) as one of the phytoalexins, was synthesized starting from (S)-lactic acid as the chiral source using Seebach’s chiral selfreproduction method.