Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 43, No. 5, 1996, pp.1073-1081
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7433
A Synthesis of New Pyrido[2',3': 4,5]thieno[2,3-c]pyridazine Derivatives

Ma. Carmen Veiga, José Ma. Quintela,* and Carlos Peinador

*Departamento de Química Fundamental e Industrial, Facultad de Ciencias, Universidad de La Coruña, Campus de A Zapateira, E-15071, La Coruña, Spain

Abstract

5-Amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carbaldehyde is formed by DIBAL reduction from the corresponding cyano precursor 5-amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carbonitrile (1). A variety of substituted pyrido[2’,3’:4,5]thieno[2,3-c]pyridazines were synthesized from 5-amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carbaldehyde (2) by Friedländer condensation with acyclic cyclic, heterocyclic or α,β-unsatured ketones and other active methylene compounds.