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Paper | Regular issue | Vol 43, No. 6, 1996, pp.1223-1228
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7428
Total Synthesis of (±)-Gericudranin A

Yoon-Jung Choi, Pil-Jong Shim, Kyung-Soo Ko, And Hee-Doo Kim*

*College of Pharmacy, Sookmyung Women's University, Yongsan-Ku, Seoul 140-742, Korea


An efficient total synthesis of (±)-gericudranin A is described. Trihydroxyacetophenone was converted to (±)-gericudranin A in seven steps via sequential protection, aldol condensation, epoxidation, cationic cyclization, regioselective C-benzylation and deprotection.