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Paper | Regular issue | Vol 43, No. 5, 1996, pp.1021-1030
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7412
1,3-Dipolar Cycloaddition of Nitriles under Microwave Irradiation in Solvent-Free Conditions

Angel Díaz-Ortiz *, Enrique Díez-Barra, Antonio de la Hoz, Andrés Moreno, Maria J. Gómez-Escalonilla, and André Loupy

*Facultad de Química, Universidad de Castilla-La Mancha, E-13071 Ciudad Real, Spain


Several nitriles were allowed to react with nitrones or nitrile oxides in the absence of solvent under microwave irradiation within 2-10 min to give 2,3-dihydro-1,2,4-oxadiazoles or 1,2,4-oxadiazoles, respectively.