Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Special issue | Vol 42, No. 2, 1996, pp.489-492
Published online, 1st January, 1970
DOI: 10.3987/COM-95-S72
The Mechanism of Configuration Retention in the Substitution Reaction of C4-Tosyloxyproline with Lithium Diarylcuprate

Kimiko Hashimoto, Yukio Shima, and Haruhisa Shirahama*

*Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan


The mechanism of configuration retention during the substitution reaction of C4-tosyloxyproline with lithium diarylcuprate was studied. Among the three possible intermediates (a~c), c has been found to be the origin of the retention mechanism.