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Paper | Special issue | Vol 42, No. 1, 1996, pp.437-443
Published online, 1st January, 1970
DOI: 10.3987/COM-95-S69
The Synthesis of 1β-Fluorocarbapenem Derivative

Masataka Ihara, Ken Satoh, Yohhei Ishida, Nobuaki Taniguchi, Yuji Tokunaga, Makoto Takemura, and Keiichiro Fukumoto

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


The synthesis of 1β-fluorocarbapenem derivative (16) was carried out starting with the 4-acetoxyazetidin-2-one (3) through the carbapenem formation utilizing the Sankyo’s procedure.