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Paper | Special issue | Vol 42, No. 1, 1996, pp.415-422
Published online, 1st January, 1970
DOI: 10.3987/COM-95-S60
Preparation of Optically Active 8,8’-Disubstituted 1,1’-Biisoquinoline

Ken-ichi Hirao, Ryuta Tsuchiya, Yasuhiro Yano, and Hirohito Tsue

*Laboratory of Organic Chemistry, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo 060-0810, Japan

Abstract

Synhesis of 1,1’-biisoquinolines having substituents in the 8,8’-positions and their resolution by hplc on a chiral column on a preparative scale are described.