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Paper | Special issue | Vol 42, No. 1, 1996, pp.325-331
Published online, 1st January, 1970
DOI: 10.3987/COM-95-S39
Briarane Diterpenes from Micronesian Gorgonians

Mark T. Hamann, Karl N. Harrison, Anthony R. Carroll, and Paul J. Scheuer

*Department of Chemistry, University of Hawaii at Manoa, 2545 Tha Mall, Honolulu, Hawaii 96822-2275, U.S.A.

Abstract

Four new briaranes, nui-inoalides A-D, (6-9) are described. They were isolated from octocorals collected in Pohnpei and Ant atoll, Micronesia. The absolute stereochemistry of the known briarane juncin E (5) was determined. Nuiinoalide A (6) and the known gemmacolides A, B, and D (2-4) exhibit immunomodulatory activity.