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Paper | Special issue | Vol 42, No. 1, 1996, pp.273-280
Published online, 1st January, 1970
DOI: 10.3987/COM-95-S18
α-Amino Ketone Synthesis from Aldehydes and N-(α-Dialkylaminoalkyl)benzotriazoles

Alan R. Katritzky, Dai Cheng, and Richard P. Musgrave

*Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, P. O. Box 117200, Gainesville, FL 32611-7200, U.S.A.


Thiazolium salt-catalyzed reactions of aldehydes with morpholino-(alkylbenzotriazoles) allow the synthesis of a variety of α-amino ketones. The relationship between reaction conditions and selectivity is discussed.