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Paper | Regular issue | Vol 43, No. 4, 1996, pp.775-780
Published online, 1st January, 1970
DOI: 10.3987/COM-95-7324
Synthesis of 4-Substituted Methyl 3-(2,3-Epoxy)propoxythiophene-2-carboxylates

Jaime Lissavetzky* and Ignacio Manzanares

*Instituto de Química Médica (C. S. I. C.), Juan de Cierva, 3, E-28006 Madrid, Spain


The synthesis of 4-substituted methyl 3-hydroxythiophene-2-carboxylates is reported. The selective O-alkylation by two methods of these compounds gives the correspondent epoxy derivatives.