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Communication | Regular issue | Vol 41, No. 9, 1995, pp.1931-1934
Published online, 1st January, 1970
DOI: 10.3987/COM-95-7165
Asymmetric Synthesis with Chiral Hydrogenolysable Amines: A New Route to Enantiopure Cyclic β-Amino Alcohols

Olivier Lingibé, Bernadette Graffe, Marie-Claude Sacquet, and Gérard Lhommet

*Université P. et M. Curie, Laboratoire de Chimie des Hétérocycles, associé au CNRS, 4 Place Jussieu, F-75252 Paris Cedex 05, France

Abstract

Enantiopure prolinol and pipecolinol have been obtained via diastereoselective chemical reduction of chiral 2,3-dihydro-6H-1,4-oxazin-2-ones (5).