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■ Inulavosin, a New Thymol Dimer with Piscicidal Activity from Inula nervosa

Takashi Yoshida, Kazuko Mori, and Guangxin He

*Faculty of Pharmaceutical Sciences, Okayama University, Tsushima, Okayama 700, Japan

Abstract

Upon the fractionation guided by piscicidal activity using the Medaka (Oryzias latipes), three piscicidal substances were isolated from the root of Inula nervosa, and were characterized as thymol and its derivatives based on the spectral analyses including 2D nmr techniques. A new piscicide, named inulavosin, was a thymol dimer with a new heterocyclic skeleton.