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Paper | Regular issue | Vol 41, No. 5, 1995, pp.1077-1084
Published online, 1st January, 1970
DOI: 10.3987/COM-95-7057
Synthesis of Egonol and (±)-Machicendiol

Yutaka Aoyagi, Toshihiko Mizusaki, Akiko Hatori, Taichi Asakura, Takashi Aihara, Sakae Inaba, Ken Hayatsu, and Akihiro Ohta*

*School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-03, Japan

Abstract

Two norneolignans, egonol (1) and (±)-machicendiol (2) , were synthesized by using the palladium-catalyzed cross-coupling reaction as a key step. This paper describes a new strategy for the preparation of norneolignans having a benzo[b]furan skeleton.