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Communication | Special issue | Vol 39, No. 2, 1994, pp.449-456
Published online, 1st January, 1970
DOI: 10.3987/COM-94-S(B)53
Investigations on the Chemistry of Berbanes 14. A Novel Stereoselective Approach to Biologically Active allo-Berbane Derivatives

Gábor Dörnyei, Csaba Szántay,* and Lajos Szabó

*Central Research Institute for Chemistry, Hungarian Academy of Sciences, H-1025 Budapest, P.O.Box 17, Hungary

Abstract

Stereoselective total synthesis of α2 adrenoceptor agents (1) and (2) with allo-berbane skeleton has been performed via Knoevenagel-type condensation of ketones (3).