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Paper | Regular issue | Vol 38, No. 7, 1994, pp.1527-1532
Published online, 1st January, 1970
DOI: 10.3987/COM-94-9706
Compared Reactivity of 3-, 5-, 6-, and 8-Aminoimidazo[1,2-a]pyridines in Combes Reaction: Access to Imidazonaphthyridines and Dipyrido[1,2-a:3‘,2‘-d]imidazole

Yves Blache, Alain Gueiffier,* Olivier Chavignon, Henry Viols, Jean Claude Teulade, and Jean Pierre Chapat

*Laboratoire de Chimie Organique Pharmaceutique, URA-CNRS, Faculté de Pharamcie, Université Montpellier I, 15 Avenue Charles Flahault, 34060 Montpellier, France

Abstract

The synthesis of imidazo[1,2-a][1,8]naphthyridines and dipyrido[1,2-a:3‘,2‘-d]imidazole by treatment of aminoimidazo[1,2-a]pyridines following the Combes procedure is described.