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Paper | Regular issue | Vol 41, No. 3, 1995, pp.523-532
Published online, 1st January, 1970
DOI: 10.3987/COM-94-6992
Synthesis of 3'-Amino-3'-deoxyadenosine from Levoglucosenone

Hideyuki Kuno*, Shigeo Niihata, Takashi Ebata, and Hajime Matsushita

*Life Science Research Laboratory, Japan Tobacco Inc., 6-2 Umegaoka, Aoba-ku, Yokohama, Kanagawa 227, Japan


A synthesis of 3’-amino-3’-deoxyadenosine (2) was developed by utilizing levoglucosenone (1) as a starting material through regio- and stereoselective cis-oxyamination of the carbon-carbon double bond.