Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 38, No. 6, 1994, pp.1237-1240
Published online, 1st January, 1970
DOI: 10.3987/COM-94-6734
Synthesis of an Optically Active 1-Azaspiro[4.4]non-8-en-7-one

Masazumi Ikeda,* Ken-ichiro Matsubayashi, Takayuki Imoto, Kaoru Kitao, Hiroyuki Ishibashi, and Tatsunori Sato

*Kyoto Pharmaceutical University, Misasagi-Shichonocho, Yamashina, Kyoto 607-8414, Japan

Abstract

The 1-azaspiro[4.4]one-8-en-7-one (7) and its (R)-9-(3,4-methylenedioxyphenyl)-substituted derivative (12) have been synthesized using an intramolecular aldol condensation of the pyrrolidine derivatives (6) and (11) as a key step.