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Paper | Regular issue | Vol 38, No. 6, 1994, pp.1273-1286
Published online, 1st January, 1970
DOI: 10.3987/COM-94-6672
Synthesis of 3-Alkynylpyridazines from 3-Trifluoromethanesulfonylpyridazines

Dominique Toussaint, Jean Suffert,* and Camille G. Wermuth

*Laboratoire de Pharmacochimie Moleculaire, (UPR 421 DU CNRS), Centre de Neurochimie du CNRS, 5, rue Blaise Pascal, 67084 Strasbourg-Cedex, France

Abstract

An efficient synthesis of 3-alkynylpyridaziens starting from the pyridazine triflates using a Pd° cross-coupling reaction is described.