Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Special issue | Vol 37, No. 1, 1994, pp.275-282
Published online, 1st January, 1970
DOI: 10.3987/COM-93-S59
Transition-Metal Binding Site of Bleomycin. Significance of the β-Aminoalaninamide Appendage in Regulating Oxygen Activation

Toru Sugiyama, Masaji Ohno, Masakatsu Shibasaki, Masami Otsuka,* Yukio Sugiura, Susumu Kobayashi, and Kenji Maeda

*Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan


A synthetic model study on the iron-binding site of bleomycin demonstrated that the dioxygen-activating properties of ligands largely depend on the characteristics of functional groups contained in the β-aminoalaninamide moiety.