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Communication | Regular issue | Vol 38, No. 3, 1994, pp.481-486
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6607
A Facile Synthesis of New Prostaglandin Analogues by Utilizing the Characteristics of the 1,2,4-Triazole Moiety

Shigeki Sano, Michiko Tanba, and Yoshimitsu Nagao*

*Faculty of Pharmaceutical Sciences, University of Tokushima, Sho-machi, Tokushima 770-8505, Japan

Abstract

Concise syntheses of some new prostaglandin analogues bearing the 1,5-disubstituted 1,2,4-triazole moiety were achieved by utilizing the characteristics of N2-substituted 3-nitro-1,2,4-triazole and/or N1-substituted 1,2,4-triazole derivatives.