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Paper | Regular issue | Vol 38, No. 3, 1994, pp.575-585
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6595
A Novel Synthesis of 2,4,5-Triarylimidazoles

Jerome F. Hayes,* Michael B. Mitchell, and Christopher Wicks

*SmithKline Beecham Pharmacuticals, Old Powder Mills, Nr Leigh, Tonbridge, Kent, TN11 9AN, U.K.


Aryl cyanides were reacted with a, a-dilithioarylnitromethanes to form 2,4,5-triarylimidazoles in good yield. An unusual cyclisation - elimination mechanism is proposed for this reaction.