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Communication | Regular issue | Vol 38, No. 1, 1994, pp.31-34
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6557
Intramolecular Diels-Alder Reaction of Benzynes: A Novel Strategy for the Construction of Tetrahydrobenzazepine Skeletons

Hiyoshizo Kotsuki,* Tadahiro Nobori, Toshihiro Asada, and Masamitsu Ochi

*Department of Chemistry, Faculty of Science, Kochi University, 2-5-1, Akebono-cho, Kochi 780-8520, Japan

Abstract

Intramolecular Diels-Alder reaction of benzynes, generated from ortho-haloaniline derivatives by the action of lithium 2,2,6,6-tetramethylpiperidide, with furans has been developed as a novel route for the construction of tetrahydrobenzazepine skeletons.