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Paper | Regular issue | Vol 38, No. 1, 1994, pp.167-175
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6550
A New Hydrolyzable Tannin from Geum japonicum and Its Antiviral Activity

Hong-Xi Xu, Shigetoshi Kadota,* Hua Wang, Masahiko Kurokawa, Kimiyasu Shiraki, Takao Matsumoto, and Tsuneo Namba

*Department of Virology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, Toyama 930-0194, Japan


A new hydrolyzable tannin, geponin, in addition to six known compounds were isolated from the aqueous extract of whole plant of Geum japonicum and their structures were determined by the use of 2D nmr. Geponin and gallic aldehyde showed potent antiviral activity against HSV-1 among the isolated seven compounds. These may contribute antiviral activity of the aqueous extract of G. japonicum.