Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 36, No. 12, 1993, pp.2681-2686
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6539
Synthesis of 3-(1’-Indanylidene)phthalides via Wittig-Horner Reaction of Dimethyl Phthalide-3-phosphonates and Their Conversion to the BCDE Ring Part of Fredericamycin A

Mitsuaki Watanabe,* Hitoshi Morimoto, and Sunao Furukawa

*Center for Instrumental Analysis, Nagasaki University, 1-14, Bunkyo-machi, Nagasaki 852-8521, Japan

Abstract

Wittig-Horner reaction of dimethyl phthalide-3-phosphonates with 1-indanones in the presence of bases was investigated. The 3-(1’-indanylidene)phthalides obtained above were transformed into dibenzo-1,4-diketospiro[4.4]nonanes, the BCDE ring system of fredericamycin A, by consecutive treatments with diisobutylaluminum hydride and pyridinium dichromate.