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Paper | Regular issue | Vol 36, No. 8, 1993, pp.1925-1932
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6411
Syntheses of 1-Benzyloxyaminoalkylphosphonates

Richard Neidlein* and Holger Keller

*Pharmazeutisch Chemishes Institut, Im Neuenheimer Feld 364, 6900 Heidelberg, Germany

Abstract

A synthesis of 1-benzyloxyaminoalkylphosphonates was achieved via ionic hydrogenation of diethyl 1-benzyloxyiminoalkylphosphonates by triethylsilane-trifluoroacetic acid. Diethyl 1-benzyloxyaminomethylphosphonate, which could not prepared by reduction, was synthesized by a simple one pot reaction.