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Communication | Regular issue | Vol 36, No. 9, 1993, pp.1945-1949
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6401
Synthesis of Original Pyrrolonaphthyridines by 1,3-Dipolar Cycloaddition Reactions of Naphthyridinium Dicyanomethylides with Dimethyl Acetylenedicarboxylate

Isabelle Cardinaud, Alain Gueiffier,* Florence Fauvelle, Jean-Claude Milhavet, and Jean-Pierre Chapat

*Laboratoire de Chimie Organique Pharmaceutique, URA-CNRS, Faculté de Pharamcie, Université Montpellier I, 15, Avenue Charles Flahault, 34060 Montpellier, France

Abstract

The pyrrolo[2,1-f][1,6]naphthyridine, pyrrolo[1,2-a][1,8]- and [1,5]naphthyridines along with their corresponding 2,3- and 1,2-dihydrocompounds are synthesized from naphthyridinium dicyanomethylides and dimethyl acetylenedicarboxylate.