Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 36, No. 8, 1993, pp.1823-1836
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6372
Synthesis of (+)-Preussin

Makoto Shimazaki, Fumiaki Okazaki, Fumihiro Nakajima, Tetsuya Ishikawa, and Akihiro Ohta*

*Tokyo College of Pharmacy , 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


A total synthesis of (+)-preussin (1), a novel antifungal agent, was achieved via asymmetric 1,3-dipolar cycloaddition of decyl methyl nitrone (2) with (-)-1-phenyl-3-buten-2-ol (3) as a key reaction.