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Paper | Regular issue | Vol 36, No. 7, 1993, pp.1625-1630
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6371
The Alkylation of 2-Amino-6-chloropurine with Alcohols by Mitsunobu Reaction for a Synthesis of Carbocyclic Guanosine Analogs

Akemi Toyota,* Nobuya Katagiri, and Chikara Kaneko

*Phamaceutical Institute, Tohoku University, Aramaki, Aoba-ku, sendai 980-8578, Japan


Mitsunobu reaction of 2-amino-6-chloropurine with various alcohols which provides a convenient method for a synthesis of carbocyclic or acyclic guanosine analogs is described.