Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 36, No. 6, 1993, pp.1399-1410
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6343
An Alternative Method for Synthesis of the CC-1065 Pharmacophore, 1,2,7,7a-Tetrahydrocycloprop[1,2-c]indol-4-one

Yuqiang Wang and J. William Lown*

*Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada


The synthesis of the CC-1065 pharmacophore, 2-(1-methylpyrrole-2-carbonyl)-1,2,7,7a-tetrahydrocycloprop[1,2-c]indol-4-one (17), is described. The methods reported here provide an alternative route for the synthesis of compounds possessing the biologically active 1,2,7,7a-tetrahydrocycloprop[1,2-c]indol-4-one (CI) functionality.