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Paper | Regular issue | Vol 36, No. 5, 1993, pp.1017-1026
Published online, 1st January, 1970
DOI: 10.3987/COM-92-9262
Synthesis of (+)-trans-Whisky Lactone, (-)-cis-Whisky Lactone, (+)-Cognac Lactone and (+)-Eldanolide

Takashi Ebata,* Katsuya Matsumoto, Hajime Yoshikoshi, Koshi Koseki, Hiroshi Kawakami, Koji Okano, and Hajime Matsushita

*Life Science Research Laboratory, Japan Tobacco Inc., 6-2, Umegaoka, Midori-ku, Yokohama, Kanagawa 227-8512, Japan


(+)-trans-Whisky lactone (5) and (-)-cis-whisky lactone (8), (+)-cognac lactone (9) and (+)-eldanolide (10) were synthesized starting from levoglucosenone (1) in optically pure states.