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Paper | Regular issue | Vol 36, No. 5, 1993, pp.1081-1089
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6277
New Alkaloids from Consolida hellespontica

Haridutt K. Desai, Balawant S. Joshi, S. William Pelletier,* Bilge Sener, Funda Bingöl, and Turan Baykal

*Institute for Natural Products Research, Department of Chemistry, The University of Georgia, Chemistry Building, Athens, Georgia 30602-2556, U.S.A.


From the aerial parts of Consolida hellespontica (Boiss.) Chater we have isolated the new diterpenoid alkaloids chellespontine (1) and azitine (4). The norditerpenoid alkaloid 1-O-methyldelphisine (7) has not been reported earlier as occurring in nature, and the aporphine alkaloid (+)-corydine (11) has been isolated for the first time in the Ranunculaceae family. Besides these, the known alkaloids delphinine (8), delphisine (9) and bullatine C (14-acetylneoline) (10) have been isolated from this plant. The structures of these alkaloids were established by chemcial correlation and spectroscopic studies.