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Paper | Regular issue | Vol 36, No. 5, 1993, pp.1047-1050
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6268
Improved Synthesis of Dihydroisoquinoline Reissert Compounds

Yvette A. Jackson, E. Kyle Stephenson, and Michael P. Cava*

*Department of Chemistry, The University of Alabama, Box 870336, Tuscaloosa Alabama 35487-0336, U.S.A.

Abstract

Conversion of a series of 3,4-dihydroisoquinolines to their corresponding Reissert compounds was improved significantly over the usual reaction conditions by buffering the reaction medium at pH 8.