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Paper | Regular issue | Vol 36, No. 4, 1993, pp.769-776
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6236
A Simple Synthesis of 2-Methoxypyridine-3-carbonitriles

Pedro Victory,* José I. Borrell, and Anton Vidal-Ferran

*Departament de Química Orgànica, CETS Institut Químic de Sarrià, Universitat Ramon Llull, Via Augusta 390, E-08017 Barcelona, Spain

Abstract

The condensation of propanedinitrile with several enals or enones in a methanol-sodium methoixde system provides a one-step route to 2-methoxypyridine-3-carbonitriles. Together with these compounds substituted 2-aminobenzene-1,3-dicarbonitriles, were obtained as by-products.