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Communication | Regular issue | Vol 36, No. 4, 1993, pp.651-654
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6211
Preparation of Novel Cyclophosphamides Derivatives of Sugars

Mitsuji Yamashita,* Chihiro Takahashi, and Kuniaki Seo

*Department of Applied Chemistry, Faculty of Engineering, Shizuoka University, 3-5-1 Johoku, Hamamatsu 432-8561, Shizuoka, Japan


Novel cyclophosphamide derivatives bearing a sugar structure were prepared by the treatment of the amino sugars from D-glucose and D-xylose with bis-(2-chloroethyl)aminophosphoric dichloride as well as with phosphoryl chloride and nucleophiles.